Nuclear and cytoplasmic expression of survivin in 67 surgically resected pancreatic cancer patients
2005
Survivin Expression in Pancreatic Cancer Patients
Sample size: 67
publication
Author Information
Author(s): Tonini G, Vincenzi B, Santini D, Scarpa S, Vasaturo T, Malacrino C, Coppola R, Magistrelli P, Borzomati D, Baldi A, Antinori A, Caricato M, Nuzzo G, Picciocchi A
Primary Institution: Cancer Research UK
Conclusion
The study corrects the expression data of survivin and Cox-2 in pancreatic cancer patients.
Supporting Evidence
- Nuclear survivin expression was positive in 37.3% of patients.
- Cytoplasmic survivin expression was positive in 44.8% of patients.
- Cox-2 expression was positive in 47.8% of patients.
- TUNEL staining showed more than 10 in 41.8% of patients.
Takeaway
This study looked at how a protein called survivin is found in people with pancreatic cancer, and it fixed some mistakes in the earlier report.
Digital Object Identifier (DOI)
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