Cognitive dysfunction in Moyamoya disease: latest developments and future directions
2024

Cognitive Dysfunction in Moyamoya Disease: Latest Developments and Future Directions

Sample size: 61 publication 10 minutes Evidence: moderate

Author Information

Author(s): Wang Xilong, Liu Ziqi, Zhou Zhenyu, Zhang Junze, Wang Yanru, He Shihao, Wang Rong

Primary Institution: Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Hypothesis

Current knowledge of cognitive impairment in Moyamoya disease is inadequate.

Conclusion

Cognitive dysfunction is common in Moyamoya disease, particularly affecting executive functions and memory.

Supporting Evidence

  • Cognitive dysfunction is prevalent in both adult and pediatric patients with Moyamoya disease.
  • Executive function is the most commonly affected cognitive domain in adults with Moyamoya disease.
  • Studies indicate that cognitive impairment in Moyamoya disease is not solely related to stroke history.

Takeaway

People with Moyamoya disease often have trouble thinking and remembering things, especially with tasks that require planning.

Methodology

The review analyzed existing studies on cognitive function in Moyamoya disease and provided recommendations for future research.

Potential Biases

Potential bias due to the limited number of studies and variability in patient demographics.

Limitations

Current studies on cognitive impairment in Moyamoya disease are limited and often lack long-term follow-up.

Participant Demographics

The review includes studies on both adult and pediatric patients with Moyamoya disease.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fnhum.2024.1502318

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