Adventitious Viral Genomes in Vaccines but Not in Vaccinees
2001
Viral Genomes in Vaccines and Their Safety
Commentary
Author Information
Author(s): Robin A. Weiss
Primary Institution: University College London
Hypothesis
Are chicken cell substrate vaccines safe from endogenous avian retroviruses?
Conclusion
The study reassures that recipients of the MMR vaccine show no evidence of infection by endogenous avian retroviruses.
Supporting Evidence
- Recipients of the MMR vaccine show no evidence of infection by endogenous avian retroviruses.
- Vaccine manufacturers were required to use eggs or CEF from leukosis-free flocks.
- Endogenous retroviruses are difficult to eliminate from live, attenuated vaccines.
Takeaway
This study says that vaccines made from chicken cells are safe because they don't infect people with harmful viruses.
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