Analysis of Lactobacillus Products for Phages and Bacteriocins That Inhibit Vaginal Lactobacilli
Author Information
Author(s): Lin Tao, Sylvia I. Pavlova, Susan M. Mou, Wen-ge Ma, Ali O. Kili
Primary Institution: University of Missouri-Kansas City
Hypothesis
Do certain Lactobacillus products release phages or bacteriocins that can inhibit vaginal lactobacilli?
Conclusion
Some vaginal lactobacilli were inhibited in vitro by phages or bacteriocins released from Lactobacillus products used by women.
Supporting Evidence
- 43 Lactobacillus strains were isolated from 26 products.
- 11 yogurt strains released phages that inhibited vaginal lactobacilli.
- 11 strains released bacteriocins that inhibited vaginal lactobacilli.
- Less than 20% of vaginal strains were lysed by phages.
Takeaway
Some foods with Lactobacillus can release tiny viruses or proteins that might stop good bacteria in the vagina from working properly.
Methodology
Lactobacillus products were tested for phages and bacteriocins that inhibit vaginal lactobacilli using various laboratory methods.
Limitations
The study was conducted in vitro, and results may not reflect in vivo conditions in humans.
Participant Demographics
The vaginal Lactobacillus strains were isolated from 27 women, including various ethnic backgrounds.
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