Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature
2008

Acral Lentiginous Melanoma of the Foot and Ankle: A Case Series

Sample size: 27 publication Evidence: moderate

Author Information

Author(s): Bristow Ivan R, Acland Katharine

Primary Institution: School of Health Sciences, University of Southampton, UK

Hypothesis

What are the common clinical factors associated with acral lentiginous melanoma (ALM) diagnosed at the ankle or below?

Conclusion

Earlier diagnosis of ALM requires education at both a patient and practitioner level.

Supporting Evidence

  • 27 cases of ALM were identified over a six-year period.
  • 33% of patients were initially misdiagnosed.
  • The average time from recognition to correct diagnosis was around 13.5 months.
  • 62% of lesions were located on the plantar surface.

Takeaway

Acral lentiginous melanoma is a rare type of skin cancer that can appear on the foot, and it often gets misdiagnosed, so it's important for both patients and doctors to be aware of it.

Methodology

A retrospective review of all patients diagnosed with ALM at a tertiary skin tumour centre over a six-year period.

Potential Biases

Data collected from a tertiary center may introduce bias as it may only include more complex cases.

Limitations

The study is based on a small cohort from a tertiary care center, which may not represent the general population.

Participant Demographics

The cohort consisted of 20 females and 7 males, with a mean age of 62.7 years, predominantly white.

Statistical Information

Confidence Interval

RR = 6.3 (95% CI 2.5–15.6) for high mole count as a risk factor.

Digital Object Identifier (DOI)

10.1186/1757-1146-1-11

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