Which variables are associated with blood glucose levels outside the target range in surgical critically ill patients? A retrospective observational study

2011

Factors Affecting Blood Sugar Levels in Critically Ill Surgical Patients

Sample size: 804 publication 10 minutes Evidence: moderate

Author Information

Author(s): Weiss Manfred, Kron Martina, Hay Birgit, Taenzer Michael, Radermacher Peter, Georgieff Michael

Primary Institution: University Hospital Medical School Ulm

Hypothesis

What variables are associated with blood glucose levels outside the target range in surgical critically ill patients?

Conclusion

Critically ill surgical patients are at an increased risk for fluctuating blood glucose concentrations, particularly if they are older and require insulin, noradrenaline, or steroids.

Supporting Evidence

Older age is associated with increased risk of blood glucose concentrations < 80 mg/dl.
Insulin administration significantly raises the risk of hypoglycemia.
Patients undergoing neurosurgery are at higher risk for hyperglycemia.

Takeaway

This study found that older patients and those receiving certain medications are more likely to have blood sugar levels that are too high or too low.

Methodology

The study surveyed critically ill surgical patients daily for blood glucose levels and other clinical variables, using logistic regression to analyze associations.