TOBFAC: The Database of Tobacco Transcription Factors
Author Information
Author(s): Rushton Paul J, Bokowiec Marta T, Laudeman Thomas W, Brannock Jennifer F, Chen Xianfeng, Timko Michael P
Primary Institution: University of Virginia
Hypothesis
The study aims to analyze tobacco transcription factors (TFs) using a large dataset of gene-space sequence reads.
Conclusion
TOBFAC is a comprehensive resource for tobacco TFs, providing data for over 2,513 TFs from 64 gene families.
Supporting Evidence
- Tobacco contains a minimum of 2,513 TFs representing all of the 64 well-characterised plant TF families.
- TOBFAC integrates available sequence information, phylogenetic analysis, and EST data with published reports on tobacco TF function.
- The database is publicly accessible and serves as a major resource for the study of gene expression in tobacco.
Takeaway
The researchers created a big database to help scientists study how tobacco plants control their genes.
Methodology
The study used methylation filtering to obtain gene-space sequence reads and developed an analytical pipeline to identify and classify tobacco TFs.
Limitations
The exact number of tobacco TFs is difficult to predict, and not all genes are present as complete sequences.
Digital Object Identifier (DOI)
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