The reliability of assigning individuals to cognitive states using the Mini Mental-State Examination: a population-based prospective cohort study
2011

Reliability of the Mini Mental-State Examination in Older Adults

Sample size: 2275 publication Evidence: moderate

Author Information

Author(s): Marioni Riccardo E, Chatfield Mark, Brayne Carol, Matthews Fiona E

Primary Institution: Department of Public Health and Primary Care, University of Cambridge

Hypothesis

The reliability of grouping individuals into cognitive states using the Mini-Mental State Examination (MMSE) has not been fully explored.

Conclusion

A state-based approach to analyzing the reliability of the MMSE provided similar results to correlation analyses.

Supporting Evidence

  • The proportion of people who remained in the same MMSE group at screen and follow-up ranged from 58% to 78%.
  • Most of the change in cognitive group occurred near the cut-points of the MMSE.
  • There was no consistently significant predictor for changing cognitive group.

Takeaway

This study looked at how well the Mini-Mental State Examination can group older people into different cognitive states, and found it does a good job.

Methodology

MMSE data were collected from 2,275 older participants, with two measurements taken approximately two months apart to investigate cognitive group changes.

Potential Biases

There is a potential for misclassification due to the ceiling effect of the MMSE.

Limitations

The study's limitations include the time between cognitive measures and the age of participants, which may affect the results.

Participant Demographics

The study included 2,275 older participants, with a higher proportion of women (63%) and a range of ages from 65 to over 90.

Statistical Information

P-Value

p<0.001

Confidence Interval

(0.84, 0.88)

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1471-2288-11-127

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