Selenium and mercury in the Brazilian Amazon: opposing influences on age-related cataracts
2011

Influence of Selenium

Sample size: 448 publication Evidence: moderate

Author Information

Author(s): Lemire Mélanie, Mergler Donna

Primary Institution: Centre de recherche du Centre hospitalier universitaire de Québec

Hypothesis

Whether dietary Se is less toxic in Hg-exposed populations remains unanswered.

Conclusion

The study found no association between selenium status and signs of selenosis despite high selenium body burdens.

Supporting Evidence

  • High selenium body burdens were observed without signs of selenosis.
  • Only 5 out of 448 participants reported diabetes.
  • Previous studies have shown no association between selenium status and diabetes in similar populations.

Takeaway

This study looked at people with high selenium levels and found that they didn't show signs of selenium poisoning, even though they had high amounts in their bodies.

Methodology

The study evaluated biomarkers of selenium status and their association with signs and symptoms of selenosis.

Limitations

The study was conducted in a specific population and may not be generalizable to other groups.

Participant Demographics

Participants were from the Amazonian population, with only 5 reporting diabetes.

Digital Object Identifier (DOI)

10.1289/ehp.1003242

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