Diffuse Maculopapular Rash: A Rare Sign of Secondary Syphilis
Author Information
Author(s): Muacevic Alexander, Adler John R, Hobbs Landon, Bardhi Redina, Shah Priyanka, Rajabi-Estarabadi Ali, Akhtar Asfa
Primary Institution: Cleveland Clinic Florida, Weston, USA
Hypothesis
Can secondary syphilis present as a diffuse maculopapular rash that mimics a drug reaction?
Conclusion
The patient was diagnosed with secondary syphilis, and treatment led to significant improvement in the rash.
Supporting Evidence
- The patient had a rash that spread from his trunk to his hands and wrists.
- Skin biopsy confirmed the presence of T. pallidum.
- The patient was treated with benzathine penicillin G, leading to significant improvement.
Takeaway
A man had a rash that looked like a drug reaction, but it turned out to be secondary syphilis, which can show up in different ways. Treating it helped his rash get better.
Methodology
The case involved a patient with a diffuse maculopapular rash, confirmed through skin biopsy and serologic testing.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
A 45-year-old man with a history of hypertension, hypercholesterolemia, and type I diabetes mellitus.
Digital Object Identifier (DOI)
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