Effect of a Web-Based Heartfulness Program on the Mental Well-Being, Biomarkers, and Gene Expression Profile of Health Care Students: Randomized Controlled Trial
2024

Heartfulness Meditation Improves Mental Well-Being in Health Care Students

Sample size: 78 publication 10 minutes Evidence: high

Author Information

Author(s): Uzun Ece, Thakur Mansee, Desai Kunal, Thimmapuram Jayaram, Patel Kamlesh D, Bhatt Deepti, Chauhan Ajay, Madhusudhan Divya, Bhatt Kashyap K, Deshpande Snehal, Budhbhatti Urvi, Joshi Chaitanya

Primary Institution: WellSpan Health

Hypothesis

Does Heartfulness meditation improve mental well-being, biomarkers, and gene expression in health care students?

Conclusion

Heartfulness meditation practice was associated with reduced depression, anxiety, and stress scores, and improved health measures in DHEA-S and IL-6 levels.

Supporting Evidence

  • The Heartfulness group showed a significant 17.35% reduction in perceived stress scores.
  • DASS-21 scores decreased significantly by 27.14% in the Heartfulness group.
  • DHEA-S levels increased significantly by 20.27% in the Heartfulness group.
  • IL-6 levels decreased significantly in both groups, with a 28.6% reduction in the Heartfulness group.
  • Gene expression analysis revealed 875 upregulated genes in the Heartfulness group.

Takeaway

Meditation can help students feel less stressed and anxious, making them happier and healthier.

Methodology

Participants were randomly assigned to either a Heartfulness meditation group or a control group, completing stress and mental health questionnaires and measuring biomarkers before and after 12 weeks.

Potential Biases

Potential unknown sources of bias including diet and personal life factors.

Limitations

The control group received no alternative activity, and many factors could influence inflammatory markers.

Participant Demographics

Health care students aged 18 or older from nursing, physiotherapy, and pharmacy programs.

Statistical Information

P-Value

P<.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.2196/65506

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