Obstructive Sleep Apnea and Kidney Injury
Author Information
Author(s): Yang Linghong, Liu Bo, Zhao Feimin, Zhou Zhangning
Primary Institution: Huzhou Central Hospital, Affiliated Central Hospital Huzhou University
Hypothesis
Is there a correlation between obstructive sleep apnea syndrome and renal injury?
Conclusion
Obstructive sleep apnea syndrome is closely related to renal injury, and they may be risk factors for each other.
Supporting Evidence
- The study included 8 trials that showed higher serum cystatin C levels in patients with obstructive sleep apnea.
- Serum creatinine levels were also found to be significantly higher in patients with obstructive sleep apnea.
- Serum urea nitrogen levels were elevated in obstructive sleep apnea patients compared to controls.
Takeaway
People who have trouble breathing while sleeping might also hurt their kidneys. This study looked at many other studies to see how they are connected.
Methodology
A meta-analysis was conducted by reviewing studies from PubMed, Embase, and Ovid-Medline databases, focusing on the correlation between obstructive sleep apnea syndrome and renal injury.
Potential Biases
All included studies had a low risk of bias.
Limitations
The study may not account for other risk factors for renal injury and is based on observational data.
Participant Demographics
The meta-analysis included 981 participants, with 612 in the case group and 369 in the control group.
Statistical Information
P-Value
p<0.01
Confidence Interval
95% CI 0.96–1.28
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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