Outcomes of Patients with Tuberculous Pleurisy
Author Information
Author(s): Shu Chin-Chung, Wang Jann-Tay, Wang Jann-Yuan, Lee Li-Na, Yu Chong-Jen
Primary Institution: National Taiwan University Hospital
Hypothesis
Does pulmonary involvement affect the in-hospital mortality rate of patients with culture-confirmed tuberculous pleurisy?
Conclusion
Patients with pulmonary involvement in tuberculous pleurisy have a higher in-hospital mortality rate compared to those with isolated pleurisy.
Supporting Evidence
- The isolated pleurisy group had a lower in-hospital mortality rate (4%) compared to the pleuro-pulmonary group (24%).
- Patients with underlying comorbidities had a higher in-hospital mortality rate.
- A typical pathology for tuberculous pleurisy on pleura biopsy was associated with better outcomes.
Takeaway
This study found that patients with lung involvement when they have tuberculous pleurisy are more likely to die in the hospital than those who only have pleurisy.
Methodology
Retrospective study analyzing hospitalized patients with culture-confirmed tuberculous pleurisy, classified into isolated pleurisy and pleuro-pulmonary groups.
Potential Biases
Selection bias due to the study being conducted in a tertiary-care referral center.
Limitations
The study is retrospective, may have missed culture-negative cases, and had a follow-up rate of less than 90%.
Participant Demographics
Patients were predominantly male, with a mean age of 52.6 years in the isolated pleurisy group and 70.4 years in the pleuro-pulmonary group.
Statistical Information
P-Value
0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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