Ceftriaxone-Resistant Salmonella in France
Author Information
Author(s): Egorova Svetlana, Timinouni Mohammed, Demartin Marie, Granier Sophie A., Whichard Jean M., Sangal Vartul, Fabre Laëtitia, Delauné Aurélia, Pardos Maria, Millemann Yves, Espié Emmanuelle, Achtman Mark, Grimont Patrick A.D., Weill François-Xavier
Primary Institution: Institut Pasteur, Paris, France
Hypothesis
The study investigates the circulation of Newport MDR-AmpC in humans, animals, and animal-derived food in France.
Conclusion
Newport MDR-AmpC isolates have caused sporadic cases and small outbreaks in humans in France from 2000 to 2005.
Supporting Evidence
- 829 Newport isolates were reported among 69,759 Salmonella clinical isolates in France from 2000 to 2005.
- 46 out of 585 human Newport isolates tested were resistant to third-generation cephalosporins.
- A small outbreak of Newport MDR-AmpC was linked to imported horse meat in 2003.
Takeaway
Some types of Salmonella that resist important antibiotics were found in people in France, likely coming from imported food.
Methodology
The study involved antimicrobial susceptibility testing on human and nonhuman Newport isolates and analysis of plasmids.
Limitations
The source of the French isolates remains unknown, and the study was limited to a specific time frame.
Participant Demographics
The isolates were primarily from the Paris metropolitan area and northern France.
Digital Object Identifier (DOI)
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