Comparing Dexmedetomidine and Clonidine in Epidural Anaesthesia
Author Information
Author(s): Bajwa Sukhminder Jit Singh, Bajwa Sukhwinder Kaur, Kaur Jasbir Singh, Gurpreet Arora, Vikramjit Gupta, Sachin Kulshrestha, Ashish Singh, Amarjit Parmar, Singh Anita, Goraya SPS
Primary Institution: Gian Sagar Medical College & Hospital, Banur, Punjab, India
Hypothesis
Is dexmedetomidine a more effective adjuvant than clonidine in epidural anaesthesia?
Conclusion
Dexmedetomidine is a better neuraxial adjuvant compared to clonidine for providing early onset of sensory analgesia, adequate sedation, and prolonged post-operative analgesia.
Supporting Evidence
- Dexmedetomidine provided a faster onset of sensory analgesia compared to clonidine.
- Patients receiving dexmedetomidine had better sedation scores than those receiving clonidine.
- The side effect profile was comparable between both groups.
Takeaway
This study found that using dexmedetomidine with pain relief medicine helps patients feel less pain and more relaxed during and after surgery compared to using clonidine.
Methodology
A prospective randomized study with 50 adult female patients undergoing vaginal hysterectomies, comparing two groups receiving either dexmedetomidine or clonidine as an adjuvant to ropivacaine.
Potential Biases
Potential bias in patient selection and allocation to treatment groups.
Limitations
The study only included female patients and may not be generalizable to other populations.
Participant Demographics
50 adult female patients aged 44 to 65 years, ASA grade I/II.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website