The evolution of anti-TNF therapy in rheumatic disease: experience, insights and advances
2011

The Evolution of Anti-TNF Therapy in Rheumatic Disease

publication Evidence: high

Author Information

Author(s): Joachim Kalden, Josef S Smolen, Paul Emery, Ferdinand C Breedveld, Bernard Combe, Georg Schett, Paul P Tak

Primary Institution: Nikolaus-Fiebiger-Zentrum, Glueckstrasse 6, 91054 Erlangen, Germany

Conclusion

Anti-TNF therapy has significantly improved the treatment of rheumatoid arthritis and other inflammatory diseases by controlling inflammation and preventing joint damage.

Supporting Evidence

  • TNF inhibitors have changed the treatment approach for rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis.
  • Early diagnosis and treatment can significantly slow or stop disease progression.
  • Combination therapy with TNF inhibitors and methotrexate can halt disease progression.

Takeaway

Doctors have found better ways to help people with arthritis by using special medicines that stop inflammation, which helps keep their joints healthy.

Digital Object Identifier (DOI)

10.1186/1478-6354-13-S1-S1

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