Investigation of Choroidal Circulation Hemodynamics Using Laser Speckle Flowgraphy After Periocular Skin Warming
2024

Choroidal Blood Flow Changes After Skin Warming

Sample size: 24 publication Evidence: moderate

Author Information

Author(s): Muacevic Alexander, Adler John R, Ujita Chihiro, Hashimoto Yuki, Noguchi Kota, Nakamura Nao, Yoshimura Miki, Ichiki Sarari, Uehara Moka, Nakazaki Aimi, Taniguchi Takanori, Yoshitomi Takeshi

Primary Institution: Fukuoka International University of Health and Welfare, Fukuoka, JPN

Hypothesis

Does periocular skin warming at 40°C affect choroidal circulation hemodynamics?

Conclusion

Periocular skin warming reduces systemic circulatory activity and choroidal blood flow velocity in healthy individuals.

Supporting Evidence

  • Choroidal blood flow velocity decreased significantly after periocular skin warming.
  • Systolic and diastolic blood pressure, heart rate, and sympathetic nerve activity also decreased.
  • Choroidal thickness increased significantly after warming.

Takeaway

Warming the skin around the eyes can help blood flow in the eyes by making the body relax.

Methodology

The study measured changes in choroidal circulation hemodynamics using laser speckle flowgraphy after warming the periocular skin of 24 healthy participants.

Potential Biases

Potential bias due to the lack of randomization and absence of a control group.

Limitations

The study lacked a control group and had a small sample size, which may affect the generalizability of the results.

Participant Demographics

24 healthy young Japanese adults, 18 women and 6 men, mean age 21.0 years.

Statistical Information

P-Value

p < 0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7759/cureus.75118

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