3-Benzoyl-1,5-dimethyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
2011

Crystal Structure of a Benzodiazepine Derivative

publication Evidence: moderate

Author Information

Author(s): Dardouri Rachida, Rodi Youssef Kandri, Ladeira Sonia, Essassi El Mokhtar, Ng Seik Weng

Primary Institution: Laboratoire de Chimie Organique Appliquée, Faculté des Sciences et Techniques Université Sidi Mohamed Ben Abdallah, Fés, Morocco

Conclusion

The compound C18H16N2O3 adopts a boat-shaped conformation with specific dihedral angles between its rings.

Supporting Evidence

  • The seven-membered ring adopts a boat-shaped conformation.
  • The dihedral angle between the phenylene and phenyl rings is 28.7°.
  • The compound was synthesized using benzoyl chloride as a reactant.

Takeaway

The study looks at a special chemical compound and how its parts are arranged in space, which helps us understand its structure better.

Methodology

The compound was synthesized using potassium t-butoxide and benzoyl chloride, and its structure was analyzed using X-ray crystallography.

Digital Object Identifier (DOI)

10.1107/S160053681100866X

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