Cefazolin Prophylaxis and Infection After Lithotripsy
Author Information
Author(s): Taheri Mohammad, Kameli Ahmad, Haghighi Ramin
Primary Institution: Mashahd University of Medical Sciences, Mashahd, Iran
Hypothesis
Does cefazolin prophylaxis reduce the rate of urinary infection after transureteral lithotripsy?
Conclusion
Cefazolin prophylaxis does not effectively reduce the infection rate following transureteral lithotripsy surgery.
Supporting Evidence
- Cefazolin did not show significant differences in preventing postoperative infection.
- E. coli was the most common bacteria found in both groups.
- Patients experienced common symptoms like flank pain and urinary complaints.
Takeaway
The study tested if giving a medicine called cefazolin before a kidney stone surgery helps prevent infections, but it didn't work.
Methodology
A double-blind, randomized clinical trial with 158 patients divided into two groups: one receiving cefazolin and the other a placebo.
Limitations
The small sample size limited the ability to identify significant differences.
Participant Demographics
The mean age was approximately 38 years, with 61.1% male participants.
Digital Object Identifier (DOI)
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