The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis
2024

Exercise Improves Inhibitory Function in Depression

Sample size: 1038 publication Evidence: high

Author Information

Author(s): Xu Zhihui, Liu Cong, Wang Peng, Wang Xing, Li Yuzhang

Primary Institution: School of Physical Education Shanghai University of Sport

Hypothesis

Does exercise improve inhibitory function in patients with major depressive disorder?

Conclusion

Exercise significantly improves inhibitory function in patients with major depressive disorder.

Supporting Evidence

  • Exercise significantly improves inhibitory function in MDD patients.
  • Other types of exercise, longer duration, and lower intensity are more effective.
  • High heterogeneity exists among studies, affecting the results.

Takeaway

Doing exercise can help people with depression think better and control their impulses.

Methodology

A systematic review and meta-analysis of randomized controlled trials assessing the impact of exercise on inhibitory function in MDD patients.

Potential Biases

High heterogeneity among studies and some studies had a high risk of bias due to lack of allocation concealment.

Limitations

The included studies did not consider disease duration, depression severity, or categorize age groups.

Participant Demographics

Participants were diagnosed with major depressive disorder, with an average age of 45 years.

Statistical Information

P-Value

p < 0.001

Confidence Interval

95% CI = 0.18–0.77

Statistical Significance

p < 0.001

Digital Object Identifier (DOI)

10.1002/brb3.70178

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