Prevalence of Helicobacter pylori in Nigerian Dyspeptic Patients
Author Information
Author(s): Abiodun Christopher Jemilohun, Jesse Abiodun Otegbayo, Samuel Olawale Ola, Olayiwola Abideen Oluwasola, Adegboyega Akere
Primary Institution: University College Hospital, Ibadan, Nigeria
Hypothesis
What is the prevalence of Helicobacter pylori among dyspeptic patients in Ibadan, Nigeria?
Conclusion
The prevalence of H. pylori among dyspeptic patients using biopsy-based methods is high in South-Western Nigeria.
Supporting Evidence
- 64% of patients tested positive for H. pylori.
- Gastritis was the most common finding at endoscopy, seen in 60.5% of patients.
- Serious gastroduodenal pathologies were documented in only 14% of patients.
- 72.2% of patients with normal endoscopic findings were H. pylori positive.
Takeaway
This study found that many people in Nigeria with stomach problems have a germ called H. pylori, which can cause issues like gastritis.
Methodology
Eighty-six adult patients with dyspepsia underwent endoscopy and gastric biopsies for histology and rapid urease test.
Limitations
The study was conducted in a single hospital and may not represent the general population of South-Western Nigeria.
Participant Demographics
39 males and 47 females, aged 23 to 85 years, mean age 49.19 years.
Statistical Information
P-Value
0.41
Statistical Significance
p<0.01
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