DOES DEPRESSION EXPLAIN COGNITIVE CHANGES IN PSYCHOTHERAPY? A MEDIATION ANALYSIS
2024

Does Depression Affect Cognitive Changes in Psychotherapy?

Sample size: 249 publication Evidence: moderate

Author Information

Author(s): Emily Post, Teresa Walker, Matthew Schurr, Brenna Renn

Primary Institution: University of Nevada Las Vegas

Hypothesis

Does depression severity mediate the relationship between psychotherapy treatment and cognitive test score changes?

Conclusion

The study found that changes in depression did not mediate cognitive performance improvements in patients receiving psychotherapy.

Supporting Evidence

  • The study involved a secondary analysis of data from older adults with major depressive disorder.
  • Participants underwent two 9-week structured psychotherapies for depression.
  • Cognitive tests included the Iowa Gambling Money Task, Digit Span Backwards, and Stroop test.
  • The Hamilton Depression Rating Scale was used to assess changes in depression symptoms.

Takeaway

This study looked at whether getting better from depression helps people think better after therapy, but it found that getting better from depression doesn't always mean better thinking skills.

Methodology

The study used data from a randomized controlled trial comparing two types of psychotherapy for depression, analyzing cognitive test scores before and after treatment.

Limitations

The findings may not apply to more cognitively impaired individuals, as the sample consisted of older adults with major depressive disorder.

Participant Demographics

Older adults with major depressive disorder, mean age 70.2 years.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.2671

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