Anti-Photoaging Effects of Soy Isoflavone Extract (Aglycone and Acetylglucoside Form) from Soybean Cake
2010
Anti-Photoaging Effects of Soy Isoflavone Extract from Soybean Cake
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Huang Chieh-Chen, Hsu Bo-Yang, Wu Nan-Lin, Tsui Wen-Huei, Lin Tzu-Ju, Su Ching-Chieh, Hung Chi-Feng
Primary Institution: Fu Jen Catholic University
Hypothesis
Can soy isoflavone extract from soybean cake protect against UVB-induced skin damage?
Conclusion
Soy isoflavone extract Fraction 3 can effectively prevent skin damage caused by UVB exposure.
Supporting Evidence
- Fraction 3 increased cell viability in UVB-exposed keratinocytes.
- Fraction 3 reduced the level of erythema and transepidermal water loss in mice.
- Fraction 3 decreased epidermal thickness after UVB exposure.
- Fraction 3 enhanced catalase activity in UVB-exposed skin.
- Fraction 3 inhibited COX-2 and PCNA expression in response to UVB.
Takeaway
This study shows that a special soy extract can help protect your skin from sun damage.
Methodology
The study involved treating human keratinocytes and mice with soy isoflavone extract and measuring various skin damage indicators after UVB exposure.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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