Etoricoxibium picrate C18H16ClN2O2S+·C6H2N3O7−
2011
Crystal Structure of Etoricoxib Picrate
publication
Evidence: moderate
Author Information
Author(s): Jasinski Jerry P., Butcher Ray J., Siddegowda M. S., Yathirajan H. S., Ramesha A. R.
Primary Institution: Keene State College
Conclusion
The study presents the crystal structure of etoricoxib picrate, revealing significant interactions and structural features.
Supporting Evidence
- The mean planes of the two pyridine rings in the bipyridine unit are twisted by 33.9° with respect to each other.
- The picrate anion interacts with the protonated N atom through a bifurcated N—H⋯(O,O) hydrogen bond.
- N—H⋯O hydrogen bonds and π–π stacking interactions create a two-dimensional network structure.
Takeaway
This study looks at the structure of a compound called etoricoxib picrate, which is made of two parts that fit together like puzzle pieces.
Methodology
The compound was synthesized by mixing etoricoxib and picric acid in a hot methanol solution, followed by recrystallization.
Digital Object Identifier (DOI)
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