Cadherin-Mediated Bt Resistance in the Sugarcane Borer
Author Information
Author(s): Yang Yunlong, Zhu Yu Cheng, Ottea James, Husseneder Claudia, Leonard B. Rogers, Abel Craig, Luttrell Randall, Huang Fangneng
Primary Institution: Louisiana State University Agricultural Center
Hypothesis
Is the down-regulation of cadherin associated with Cry1Ab resistance in Diatraea saccharalis?
Conclusion
The study found that down-regulation of the cadherin gene DsCAD1 is associated with resistance to Cry1Ab in the sugarcane borer.
Supporting Evidence
- Cadherin expression was significantly lower in Cry1Ab-resistant strains.
- RNA interference confirmed the role of cadherin in susceptibility to Cry1Ab.
- Total alkaline phosphatase activity was similar between susceptible and resistant strains.
Takeaway
The sugarcane borer can resist a type of pesticide because it has less of a certain protein that the pesticide usually binds to.
Methodology
The study involved comparing gene expression levels and conducting RNA interference to assess the role of cadherin in Cry1Ab resistance.
Limitations
The study may not account for other potential resistance mechanisms beyond cadherin expression.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website