Flavonoid Fisetin Alleviates Ovarian Aging of Laying Chickens by Enhancing Antioxidant Capacity and Glucose Metabolic Homeostasis
2024

Fisetin Improves Ovarian Health in Aging Chickens

Sample size: 30 publication 10 minutes Evidence: high

Author Information

Author(s): Yang Zhaoyu, Zhang Jiaxuan, Yuan Qiongyu, Wang Xinyu, Zeng Weidong, Mi Yuling, Zhang Caiqiao, Zoidis Evangelos

Primary Institution: Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, China

Hypothesis

Fisetin provides protection against oxidative damage in aging laying chickens.

Conclusion

Fisetin supplementation can alleviate ovarian oxidative stress and improve egg production in aging laying chickens.

Supporting Evidence

  • Fisetin improved egg production and eggshell quality in aging laying chickens.
  • Fisetin reduced the rate of follicular atresia and promoted ovarian cell proliferation.
  • Fisetin elevated serum estrogen and progesterone levels in aging chickens.
  • Fisetin enhanced the activity of antioxidant enzymes in ovarian tissues.

Takeaway

Fisetin is like a superhero for aging chickens, helping them lay more eggs and keeping their ovaries healthy.

Methodology

The study involved a 21-day feeding trial with 30 aging laying chickens divided into control and fisetin groups, measuring egg production and ovarian health.

Potential Biases

Potential bias in the selection of chickens and environmental conditions during the trial.

Limitations

The study was limited to a specific breed of chickens and a short feeding duration.

Participant Demographics

Hyline White laying chickens, aged 580 days.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.3390/antiox13121432

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication