Effects of Ketone Esters on Older Adults
Author Information
Author(s): Stubbs Brianna, Stephens Elizabeth, Senadheera Chatura, Peralta Sawyer, Diaz Stephanie Roa, Silverman-Martin Wendie, Alexander Laura, Newman John
Primary Institution: Buck Institute for Research on Aging
Hypothesis
Do ketone esters modulate aging biology mechanisms and clinical outcomes relevant to frailty in older adults?
Conclusion
The study found no statistically significant differences in physical function, cognitive function, or quality of life between the ketone esters group and the placebo group.
Supporting Evidence
- The study involved 30 older adults who were randomly assigned to receive either ketone esters or a placebo.
- Exploratory outcomes included physical function, cognitive function, and quality of life.
- Results showed no significant differences between the ketone esters group and the placebo group.
Takeaway
This study looked at whether a special drink could help older people feel better and function well, but it didn't find any big differences between those who drank it and those who didn't.
Methodology
A randomized, placebo-controlled, double-blinded, parallel-group pilot trial over 12 weeks with daily ingestion of ketone esters or placebo.
Limitations
The study had a small sample size and was exploratory in nature.
Participant Demographics
Community-dwelling older adults (≥ 65 years), independent in activities of daily living, with no unstable medical conditions.
Digital Object Identifier (DOI)
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