Bacteremia Caused by Mycobacterium wolinskyi
Author Information
Author(s): Chen Yu-Chuan, Jou Ruwen, Huang Wei-Lun, Huang Shao-Tsung, Liu Keng-Chang, Lay Chorng-Jang, Chang Shu-Mei, Tseng Chih-En, Lai Chun-Liang, Su Yu-Chieh
Primary Institution: Buddhist Tzu Chi Dalin General Hospital, Chiayi, Taiwan
Hypothesis
Can Mycobacterium wolinskyi cause bacteremia in immunocompromised patients?
Conclusion
The case suggests that immunocompromised patients may be vulnerable to infection by rapidly growing mycobacterium such as M. wolinskyi.
Supporting Evidence
- The patient had a history of non-Hodgkin lymphoma and received chemotherapy.
- Laboratory tests showed a significant increase in C-reactive protein levels.
- Cultures from blood and synovial fluid tested positive for M. wolinskyi.
- The isolate showed 99% similarity to M. wolinskyi based on genetic analysis.
- The patient responded to a combination of antimicrobial therapies.
Takeaway
A woman with cancer got a serious infection from a germ called Mycobacterium wolinskyi, which usually doesn't cause problems unless your immune system is weak.
Methodology
The study involved diagnosing the infection using molecular diagnostic tools and culturing blood and synovial fluid samples.
Limitations
Only one case is reported, limiting the generalizability of the findings.
Participant Demographics
A 22-year-old woman with non-Hodgkin lymphoma.
Digital Object Identifier (DOI)
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