Burden of Melanoma in China from 1990 to 2021
Author Information
Author(s): Yu Lingling, Yan Fanshu, Qi Jinlei, Wang Lijun, Zhou Maigeng, Yin Peng
Primary Institution: National Center for Chronic and Non-Communicable Diseases Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Hypothesis
This study aimed to investigate the burden of melanoma at both national and subnational levels in China.
Conclusion
China has experienced a substantial increase in the burden of melanoma from 1990 to 2021.
Supporting Evidence
- Over the past 30 years, the age-standardized incidence rate of melanoma in China has shown an upward trend.
- The ASIR of melanoma in 2021 was 0.7 per 100,000, representing an increase of 89.2% from 1990.
- Among younger adults aged <60 years, melanoma was more common in men, whereas among older adults aged >60 years, it was more common in women.
- The ASIR was higher in the coastal provinces in 2021.
- Total numbers of death and DALYs of melanoma increased over the study period, mainly driven by population aging in China.
Takeaway
Melanoma cases in China have been rising, especially among older adults, and more needs to be done to help prevent and treat it.
Methodology
The study used annual melanoma data from the Global Burden of Disease 2021 China subnational study and employed joinpoint regression models to evaluate trends.
Potential Biases
Potential biases in the decomposition analysis due to the selection of reference population.
Limitations
The study relies on GBD data, which may have fewer sources specific to melanoma in China, potentially affecting the precision of the estimates.
Participant Demographics
The study analyzed data across 33 province-level administrative units in China, focusing on age and sex.
Statistical Information
Confidence Interval
95% UI: 0.4–0.9
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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