Identifying systematic reviews of the adverse effects of health care interventions
2006

Identifying Systematic Reviews of Adverse Effects

Sample size: 257 publication Evidence: moderate

Author Information

Author(s): Golder Su, McIntosh Heather M, Loke Yoon

Primary Institution: Centre for Reviews and Dissemination (CRD), University of York

Hypothesis

Can systematic reviews of adverse effects be identified quickly and easily in major databases?

Conclusion

Searching major databases for systematic reviews of adverse effects is more challenging than expected due to inconsistent terminology and inadequate indexing.

Supporting Evidence

  • Out of 3635 records screened, 257 met the inclusion criteria.
  • The precision of searches in CDSR was low, ranging from 0% to 3%.
  • Hand searching identified additional relevant systematic reviews that were missed by the search strategies.

Takeaway

The study tried to find reviews about the bad effects of treatments but found it really hard because the words used to describe them were all mixed up.

Methodology

The study involved searching DARE and CDSR databases for systematic reviews published from 1994 to 2005, using various search strategies.

Limitations

The study was limited to CDSR and DARE, which may not include all systematic reviews, and the low number of reviews in CDSR limited analysis.

Digital Object Identifier (DOI)

10.1186/1471-2288-6-22

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