Prognostic Factors in Renal Cell Carcinoma After Surgery
Author Information
Author(s): Zubac Dragomir P, Bostad Leif, Seidal Tomas, Wentzel-Larsen Tore, Haukaas Svein A
Primary Institution: Department of Surgical Sciences, University of Bergen, Norway
Hypothesis
Interactions between lymph node invasion, synchronous distant metastases, and venous invasion may predict outcomes for patients with renal cell carcinoma after radical nephrectomy.
Conclusion
Lymph node invasion, synchronous distant metastases, erythrocyte sedimentation rate, and venous invasion are independently associated with cancer-specific survival after surgery.
Supporting Evidence
- Lymph node invasion was diagnosed in 21 of 196 patients.
- The presence of synchronous distant metastases significantly affected survival.
- Venous invasion was associated with a higher risk of having distant metastases.
Takeaway
This study looked at how certain factors affect survival in kidney cancer patients after surgery. It found that the status of lymph nodes is very important for predicting how well patients will do.
Methodology
The study analyzed data from 196 patients who underwent radical nephrectomy, examining factors like lymph node invasion, distant metastases, and venous invasion.
Limitations
The study is retrospective and includes patients from 1985 to 1994, which may not reflect current practices.
Participant Demographics
{"mean_age":66.4,"gender_distribution":{"male":110,"female":86}}
Statistical Information
P-Value
p < 0.001
Statistical Significance
p < 0.001
Digital Object Identifier (DOI)
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