Anti-Diabetic Effects of Sorbus decora Extract
Author Information
Author(s): Vianna Rose, Brault Antoine, Martineau Louis C., Couture Réjean, Arnason John T., Haddad Pierre S.
Primary Institution: Université de Montréal
Hypothesis
Does the ethanolic crude extract of Sorbus decora have anti-diabetic effects in vivo?
Conclusion
The ethanolic crude extract of Sorbus decora shows anti-hyperglycemic and insulin-sensitizing activity in animal models of diabetes.
Supporting Evidence
- Sorbus decora increased glucose transport in skeletal muscle cells in culture.
- Sorbus decora extract significantly decreased glycemia in Type 1 diabetic rats.
- Sorbus decora extract reduced insulin resistance in pre-diabetic rats.
- Sorbus decora extract decreased glycemia in KK-Ay Type 2 diabetic mice.
Takeaway
This study found that a plant called Sorbus decora can help lower blood sugar levels in diabetic rats and mice.
Methodology
The study used three animal models of diabetes to evaluate the effects of Sorbus decora extract on blood glucose levels.
Limitations
Data variability prevented the assignment of statistical significance in some findings.
Participant Demographics
Male Sprague-Dawley rats and KK-Ay mice were used in the study.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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