Organic Papers
2011
(1S,3S)-Methyl 2-benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
publication
Evidence: moderate
Author Information
Author(s): Naicker Tricia, Govender Thavendran, Kruger Hendrik G., Maguire Glenn E. M.
Primary Institution: University of KwaZulu–Natal
Conclusion
The title compound crystallizes in a monoclinic symmetry and exhibits a half-chair conformation in its heterocyclic ring.
Supporting Evidence
- The compound is a precursor to chiral catalysts with a tetrahydroisoquinoline backbone.
- Intermolecular C—H⋯O interactions help construct a three-dimensional network in the crystal.
- The absolute stereochemistry was confirmed by proton NMR spectroscopy.
Takeaway
This study looks at a special chemical compound that can help make other useful chemicals. It has a unique shape that helps it fit together in a certain way.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
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