3-Amino-4-[4-(dimethylamino)phenyl]-4,5-dihydro-1,2,5-thiadiazole 1,1-dioxide
2011
Study of a Thiadiazole Compound
publication
Evidence: moderate
Author Information
Author(s): Arslan N. Burcu, Ertürk Aliye Gediz, Kazak Canan, Bekdemir Yunus
Primary Institution: Ondokuz Mayıs University
Hypothesis
The study verifies the preference of the enamine-imine tautomeric form in the solid state.
Conclusion
The compound exists in the amine tautomeric form and forms hydrogen bonds in the crystal structure.
Supporting Evidence
- The dihedral angle between the benzene and thiadiazolidine rings is 66.54°.
- Molecules are linked by hydrogen bonds into a layer parallel to the ac plane.
- The study confirms the existence of the compound in the amine tautomeric form.
Takeaway
This study looks at a specific chemical compound and how its molecules stick together in a solid form.
Methodology
The compound was synthesized using sodium cyanide and p-N,N-dimethyl benzaldehyde in a microwave.
Digital Object Identifier (DOI)
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