Physical Function and Mitochondrial Bioenergetics in People Living with HIV and Cancer
Author Information
Author(s): Ryan Alice, Griffith Kathleen, Jaber Sausan
Primary Institution: University of Maryland School of Medicine
Hypothesis
The study aims to determine differences in physical fitness and bioenergetic health between older adults living with HIV without and with a history of cancer.
Conclusion
The study found no significant differences in bioenergetic parameters between people living with HIV and those with a history of cancer, although there was a trend suggesting higher reliance on fatty acid oxidation in the latter group.
Supporting Evidence
- There were no significant differences in physical fitness measures between people living with HIV and those with a history of cancer.
- The study included a total of 34 participants with a mean age of 64 years.
Takeaway
The study looked at how fit older adults with HIV and cancer are, and found that while they are similar in many ways, those with cancer might use a different energy source.
Methodology
Participants underwent a cancer-specific geriatric assessment and physical function testing, with a subset having their platelets analyzed for bioenergetic functions.
Participant Demographics
Participants were predominantly male (100%) and 82% African American, with a mean age of 64 years.
Digital Object Identifier (DOI)
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