The Exception That Proves the Rule: An Interview with Jenny Graves
2008

Interview with Jenny Graves on X-inactivation and Evolution

publication

Author Information

Author(s): Jane Gitschier

Primary Institution: University of California San Francisco

Hypothesis

How does X-inactivation evolve in marsupials compared to other mammals?

Conclusion

Jenny Graves' research reveals that X-inactivation in marsupials operates differently than in other mammals, providing insights into evolutionary processes.

Supporting Evidence

  • Graves' work on monotremes and marsupials has led to insights into the evolution of sex chromosomes.
  • She discovered that DNA methylation is not important in marsupials, contrary to expectations.
  • Graves emphasizes the importance of evolutionary thinking in understanding genetic functions.

Takeaway

Jenny Graves studies unique Australian animals to understand how their genes work differently, especially how they handle X-inactivation.

Methodology

Interview format discussing research findings and personal experiences.

Digital Object Identifier (DOI)

10.1371/journal.pgen.1000063

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication