Association between composite dietary antioxidant indices and anemia: NHANES 2003–2018
2025

Dietary Antioxidants and Anemia

Sample size: 33914 publication 10 minutes Evidence: high

Author Information

Author(s): Wu Qian, Wang Zhiyu, Xia Jieyu, Xu Hui, Huang Gang, Feng Guangyong, Gou Xiaoxia

Primary Institution: The Second Affiliated Hospital of Zunyi Medical University

Hypothesis

Higher CDAI scores would correlate with decreased prevalence of anemia.

Conclusion

Higher levels of dietary antioxidants are linked to a lower prevalence of anemia.

Supporting Evidence

  • 10.07% of participants were diagnosed with anemia.
  • Each increase in CDAI level was linked to a 3% lower risk of anemia.
  • Subgroup analysis showed significant protective effects of CDAI in male non-smokers and non-diabetic individuals.

Takeaway

Eating foods rich in antioxidants can help prevent anemia, which is when you don't have enough red blood cells.

Methodology

The study used data from the NHANES database and analyzed the relationship between CDAI and anemia using logistic regression.

Potential Biases

Potential recall bias due to self-reported dietary intake.

Limitations

The study's cross-sectional design limits causal inferences, and dietary data may be subject to recall bias.

Participant Demographics

Participants included a diverse population from the NHANES database, with a mean age of 47.35 years.

Statistical Information

P-Value

<0.001

Confidence Interval

95%CI: 0.95–0.98

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1371/journal.pone.0316397

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