2,4-Bis(4-propoxyphenyl)-3-azabicyclo[3.3.1]nonan-9-one
2011
Study of a Bicyclic Compound's Structure
publication
Evidence: moderate
Author Information
Author(s): Parthiban P., Ramkumar V., Jeong Yeon Tae
Primary Institution: Pukyong National University
Hypothesis
The study aims to establish the stereochemistry of the synthesized biologically potent bicyclic compound.
Conclusion
The title compound exists in a twin-chair conformation with equatorial orientations of the 4-propoxyphenyl groups.
Supporting Evidence
- The molecule has a crystallographic mirror plane bisecting it.
- The dihedral angle between the 4-propoxyphenyl groups is 31.58°.
- The piperidine ring adopts a near ideal chair conformation.
Takeaway
The researchers looked at the shape of a special molecule to understand how it might work in the body.
Methodology
The compound was synthesized and its crystal structure was analyzed using X-ray diffraction.
Digital Object Identifier (DOI)
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