Editorial for Special Issue “Cellular Senescence: Recent Cellular Advances and Discoveries”
2024
Recent Advances in Cellular Senescence
Editorial
Author Information
Author(s): Crasta Karen Carmelina, Faggioli Francesca
Primary Institution: National University of Singapore
Conclusion
The study highlights the complex role of cellular senescence in health and disease, emphasizing its implications for aging and cancer therapy.
Supporting Evidence
- Cellular senescence can prevent damaged cells from proliferating, acting as a barrier against cancer.
- Senescent cells can influence their environment through a secretome that can either promote inflammation or aid in tissue repair.
- Long non-coding RNAs have been identified as important modulators in senescence.
- Alterations in ion channel activity may influence the onset and progression of senescence.
- Extracellular vesicles play a critical role in intercellular communication during senescence.
Takeaway
Cells can stop dividing and enter a state called senescence, which can help prevent cancer but also contribute to aging and other diseases.
Digital Object Identifier (DOI)
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