Mitochondrial Energetics and Muscle Power in Older Adults
Author Information
Author(s): Mau Theresa, Kramer Philip, Coen Paul, Hepple Russell, Kritchevsky Stephen, Newman Anne, Cawthon Peggy, Cummings Steven
Hypothesis
Mitochondrial energetics are associated with leg power and cardiorespiratory fitness in older adults.
Conclusion
Mitochondrial function is linked to leg power in older adults, particularly in men.
Supporting Evidence
- Max OXPHOS was associated with leg power for both women and men.
- ATPmax was associated with leg power for men but not significant for women.
Takeaway
This study found that how well our muscles use energy is important for how strong our legs are, especially for older men.
Methodology
Vastus lateralis biopsies were collected, and mitochondrial respiration and ATP production were measured, along with leg power and VO2peak assessments.
Participant Demographics
Older adults aged 70–94 years, 59.2% women.
Statistical Information
P-Value
p <.001 for Max OXPHOS in women; p <.050 for Max OXPHOS in men; p <.05 for ATPmax in men.
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website