Finding Cancer Clues in Databases
Author Information
Author(s): Djamel Medjahed, Peter F. Lemkin, Gary W. Smythers, David J. Munroe
Primary Institution: National Cancer Institute at Frederick
Hypothesis
Can publicly accessible databases help identify cancer markers?
Conclusion
The study developed a web-accessible repository to analyze cancer-related proteins and their expression in different tissues.
Supporting Evidence
- The study created VIRTUAL2D, a database for analyzing protein characteristics.
- TMAP was developed to visualize protein expression in cancer tissues.
- More than 18,000 gene products were included in the comparative analysis.
Takeaway
Researchers created a tool to help find cancer markers by looking at proteins in different tissues, like a treasure map for scientists.
Methodology
The study used web-accessible databases to analyze protein expression and developed tools for comparative analysis.
Potential Biases
Not all libraries have the same quality of expression data.
Limitations
The quality of the underlying databases affects the reliability of the findings.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website