Quantifying the Impact of Deprivation on Preterm Births: A Retrospective Cohort Study
2011

Impact of Deprivation on Preterm Births

Sample size: 39873 publication 10 minutes Evidence: high

Author Information

Author(s): David Taylor-Robinson, Umber Agarwal, Peter J. Diggle, Mary Jane Platt, Bill Yoxall, Zarko Alfirevic

Primary Institution: University of Liverpool

Hypothesis

There would be differential rates of preterm birth by socioeconomic status, related to individual level risk factors.

Conclusion

Deprivation has a significant impact on preterm birth rates in low risk women, related to low maternal weight and smoking.

Supporting Evidence

  • Preterm birth rates increased with deprivation, reaching 1.6% in the most deprived quintile.
  • Being underweight and smoking were independently associated with preterm birth in the low risk group.
  • Preterm birth was five times more likely in the high risk group.

Takeaway

If a mom is from a poorer area, she might have a higher chance of having her baby too early, especially if she smokes or is underweight.

Methodology

Retrospective cohort study analyzing data from 39,873 women in Liverpool, UK, from 2002–2008.

Potential Biases

Response bias may exist in self-reported smoking status.

Limitations

The study is hospital-based rather than population-based, and relies on retrospective data which may introduce bias.

Participant Demographics

The study population was predominantly from deprived areas, with 63% in the most deprived quintile.

Statistical Information

P-Value

p<0.01

Confidence Interval

CI95 1.4 to 1.8

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0023163

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