Chitosan-Based Multifunctional Biomaterials as Active Agents or Delivery Systems for Antibacterial Therapy
2024

Chitosan-Based Biomaterials for Antibacterial Therapy

publication Evidence: high

Author Information

Author(s): Wang Meng, Wang Yue, Chen Geyun, Gao Hongyu, Peng Qiang, Janorkar Amol V.

Primary Institution: State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Hypothesis

This work aims to elucidate the biological properties of chitosan and its derivatives and to track their clinical applications.

Conclusion

Chitosan and its derivatives show significant potential as antibacterial agents and drug delivery systems.

Supporting Evidence

  • Chitosan has good biocompatibility and biodegradability.
  • Chitosan exhibits strong antibacterial activity against various bacteria.
  • Chitosan can be modified to enhance its properties and applications.
  • Chitosan-based materials can be used for drug delivery systems.

Takeaway

Chitosan is a natural material that can help fight bacteria and deliver medicine effectively.

Methodology

The review summarizes previous studies on chitosan and its derivatives, discussing their functions, advantages, disadvantages, and future directions.

Limitations

The limited solubility of chitosan and the lack of clinical studies on its derivatives are significant drawbacks.

Digital Object Identifier (DOI)

10.3390/bioengineering11121278

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication