Hydrogen Bonding Patterns in Trimethoprim Derivatives
Author Information
Author(s): Muthiah Packianathan Thomas, Francis Savarimuthu, Rychlewska Urszula, Warżajtis Beata
Primary Institution: Bharathidasan University
Hypothesis
The study investigates the hydrogen bonding networks in the crystal structures of trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate.
Conclusion
The hydrogen-bonded networks in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate are remarkably similar to their respective aliphatic analogues.
Supporting Evidence
- The study identifies specific hydrogen bonding motifs in the crystal structures.
- Trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate exhibit similar hydrogen bonding patterns.
- The findings contribute to the understanding of crystal engineering and supramolecular chemistry.
Takeaway
This study looks at how certain molecules stick together using hydrogen bonds, which are like tiny magnets. It found that two similar molecules behave in the same way when they form crystals.
Methodology
The study involved analyzing the crystal structures of trimethoprim derivatives using X-ray crystallography.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website