Reference Intervals for Glycated Albumin and Diabetes Ratios
Author Information
Author(s): Yusra Al-Lahham, Waldemar Volanski, Liana Signorini, Ademir Luiz do Prado, Glaucio Valdameri, Vivian Rotuno Moure, Marciane Welter, Alexessander C. Alves, Marcel Henrique Marcondes Sari, Fabiane Gomes de Moraes Rego, Geraldo Picheth
Primary Institution: Federal University of Paraná, Curitiba, Brazil
Hypothesis
To establish reference intervals for serum glycated albumin and its ratios in a Euro-Brazilian population.
Conclusion
The study established reference intervals for glycated albumin and its ratios, which are relevant for diabetes management in Euro-Brazilian patients.
Supporting Evidence
- The study included a diverse sample of 1075 participants across different age groups and conditions.
- GA and AGI ratios demonstrated high sensitivity and specificity for differentiating between diabetes types.
- The established reference intervals align with those from other Caucasian populations.
Takeaway
This study helps doctors understand how to use glycated albumin levels to manage diabetes better, especially in different groups of people.
Methodology
A cross-sectional study using receiver operating characteristic curve analysis to determine reference intervals for various diabetes types.
Limitations
The study did not analyze complications of diabetes or the performance of biomarkers throughout the entire gestational period.
Participant Demographics
Participants included children (6-14 years), adults (21-62 years), and pregnant women (14-44 years) from a Euro-Brazilian population.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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