Intake of vegetables, fruits, beta-carotene, vitamin C and vitamin supplements and cancer incidence among the elderly: a prospective study
1992

Diet and Cancer Risk in the Elderly

Sample size: 11580 publication Evidence: moderate

Author Information

Author(s): A. Shibata, A. Paganini-Hill, R.K. Ross, B.E. Henderson

Primary Institution: University of Southern California, School of Medicine

Hypothesis

Does dietary intake of vegetables, fruits, beta-carotene, and vitamin C affect cancer incidence among the elderly?

Conclusion

The study found that while dietary factors did not show a protective effect against cancer in men, certain dietary intakes were associated with reduced cancer risks in women.

Supporting Evidence

  • 1,335 cancer cases were diagnosed during the study period.
  • Vitamin C supplement use was inversely associated with bladder cancer risk in men.
  • Women showed reduced cancer risks for all sites combined with higher intake of fruits and vegetables.

Takeaway

Eating more fruits and vegetables might help women lower their chances of getting cancer, but it didn't seem to help men in the same way.

Methodology

A cohort study followed 11,580 elderly residents from a retirement community over eight years, assessing their dietary intake and cancer incidence.

Potential Biases

Potential bias due to self-reported dietary habits and the possibility of differential recall between genders.

Limitations

The study may have missed some cancer cases and relied on self-reported dietary information, which can be inaccurate.

Participant Demographics

The cohort was primarily Caucasian, upper-middle socioeconomic class, with about two-thirds being women.

Statistical Information

P-Value

0.55 for bladder cancer in men; 0.57 for colon cancer in women

Confidence Interval

95% C.I. 0.31-0.98 for bladder cancer; 95% C.I. 0.35-0.92 for colon cancer

Statistical Significance

p<0.05

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