Analyzing Heart Strain with MRI
Author Information
Author(s): Kadiyala Madhavi, Toole Rena, Bertman Kathleen, Pollack Simcha, Reichek Nathaniel
Primary Institution: Saint Francis Hospital, The Heart Center, Roslyn, NY, USA
Hypothesis
We sought to determine normal gender-specific strain values in healthy subjects using Feature Tracking (FT-MRI).
Conclusion
FT-MRI provides consistent values for global and regional strains in three dimensions from conventional MRI images, showing significant variation among genders.
Supporting Evidence
- The peak global strains were significantly different between genders.
- There was a significant mid to apical gradient in both endocardial and epicardial strains.
- Strains were significantly associated with height, weight, left ventricular end diastolic volume, and ejection fraction.
Takeaway
This study used a special MRI technique to measure how the heart strains during beating, finding that men and women have different strain values.
Methodology
Strains were obtained with FT-MRI in 60 normal subjects, using semi-automated tracing of heart borders.
Participant Demographics
29 men and 31 women with a mean age of 54 years.
Statistical Information
P-Value
p<0.00001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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