2-[(E)-2-(4-Ethoxyphenyl)ethenyl]-1-methylpyridinium 4-chlorobenzenesulfonate monohydrate
2011
Crystal Structure of a Quaternary Ammonium Compound
publication
Evidence: moderate
Author Information
Author(s): Chantrapromma Suchada, Chanawanno Kullapa, Fun Hoong-Kun
Primary Institution: Prince of Songkla University
Hypothesis
The study investigates the crystal structure and biological activity of a specific pyridinium derivative.
Conclusion
The synthesized compound is moderately active against MRSA but inactive against susceptible Staphylococcus aureus.
Supporting Evidence
- The compound was synthesized from a previously reported procedure.
- It showed moderate activity against MRSA with a MIC value of 75 µg/ml.
- The crystal structure was determined using X-ray diffraction techniques.
Takeaway
The researchers made a new compound and found it can fight some germs but not others.
Methodology
The compound was synthesized and its crystal structure was determined using X-ray diffraction.
Digital Object Identifier (DOI)
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