The Impact of Vaccination on COVID-19 Outcomes in Vietnam
Author Information
Author(s): Nguyen Ngoc-Lan Thi, Nguyen Hien Thi Thu, Le-Quy Vang, To Thu-Ba, Tran Huy Thinh, Nguyen Tuan Duc, Hoang Yen, Nguyen Anh-Thu, Dam Lan Thi Phuong, Nguyen Nhat-Linh, Dinh-Xuan Anh Tuan, Ta Thanh-Van
Primary Institution: Hanoi Medical University Hospital
Hypothesis
This study aimed to assess the effectiveness of the COVID-19 vaccine on the outcomes of patients in three hospitals in Vietnam.
Conclusion
Vaccination reduced mortality and both hospitalization length and disease severity in COVID-19 survivors, especially the older and patients with chronic comorbidities.
Supporting Evidence
- The unvaccinated group had a higher proportion of severe conditions than the fully vaccinated group (12% vs. 3%).
- 48% of participants had at least one comorbidity.
- The vaccinated groups had higher cured rates than the unvaccinated group (64.4%, 71.3%, and 67.7% for partially vaccinated, fully vaccinated, and boosted groups, respectively, vs. 56.8%).
- Mean hospitalization duration was shorter in vaccinated groups compared to unvaccinated (8, 10, and 7 days for partially vaccinated, fully vaccinated, and boosted groups, respectively, vs. 11 days).
- Age was identified as the most crucial predictor of critical illness, followed by vaccination status and comorbidities.
Takeaway
Getting vaccinated helps people who get COVID-19 get better faster and have fewer serious problems, especially older people and those with other health issues.
Methodology
An observational study involving 3102 confirmed COVID-19 patients classified by vaccination status and analyzed using regression models.
Potential Biases
Potential biases due to retrospective data collection and missing information.
Limitations
The study collected data retrospectively, which may include missing information and did not evaluate all factors affecting outcomes.
Participant Demographics
The median age was 46 years, with 47% males and 53% females; 57% were older than 50, and 37% had at least one comorbidity.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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