Implementation of Malaria Prevention in Pregnancy in Senegal
Author Information
Author(s): Olliaro Piero L, Delenne Henriette, Cisse Moustafa, Badiane Malick, Olliaro Alberto, Vaillant Michel, Brasseur Philippe
Primary Institution: UNICEF/UNDP/WB/WHO Special Programme for Research and Training in Tropical Diseases (TDR)
Hypothesis
Does intermittent preventive treatment with sulphadoxine/pyrimethamine reduce the incidence of malaria and low birth weight in pregnant women?
Conclusion
The implementation of IPTp-SP was high, but it did not significantly reduce maternal malaria or low birth weight.
Supporting Evidence
- 69% of women attended the antenatal clinic at least three times.
- 95% of women received at least one dose of SP.
- Low birth weight prevalence was 10.8% pre-IPTp and 7.7% during IPTp deployment.
Takeaway
This study looked at how giving pregnant women medicine to prevent malaria worked in a small village in Senegal. They found that many women got the medicine, but it didn't really change how often they got malaria or how much their babies weighed.
Methodology
Data was collected from antenatal clinic registries and analyzed for women attending the clinic from 2000 to 2007.
Potential Biases
Data redundancy in record keeping may lead to inaccuracies in reported outcomes.
Limitations
The study did not assess placental malaria and the effects of other concurrent interventions were not controlled for.
Participant Demographics
Women attending the antenatal clinic, median age 28 years, with a range of gravidity from 0 to 14.
Statistical Information
P-Value
0.12
Confidence Interval
95% CI not provided
Statistical Significance
p = 0.12
Digital Object Identifier (DOI)
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